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Research Article

Analysis of the Protein Kinase A-Regulated Proteome of Cryptococcus neoformans Identifies a Role for the Ubiquitin-Proteasome Pathway in Capsule Formation

J. M. H. Geddes, M. Caza, D. Croll, N. Stoynov, L. J. Foster, J. W. Kronstad
Andrew J. Alspaugh, Invited Editor, Françoise Dromer, Editor
J. M. H. Geddes
aDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
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M. Caza
bMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada
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D. Croll
bMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada
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N. Stoynov
cCentre for High-throughput Biology, University of British Columbia, Vancouver, BC, Canada
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L. J. Foster
cCentre for High-throughput Biology, University of British Columbia, Vancouver, BC, Canada
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J. W. Kronstad
aDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
bMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada
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Andrew J. Alspaugh
Duke University Medical Center
Roles: Invited Editor
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Françoise Dromer
Institut Pasteur
Roles: Editor
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DOI: 10.1128/mBio.01862-15
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Article Information

DOI 
https://doi.org/10.1128/mBio.01862-15
PubMed 
26758180

Published By 
American Society for Microbiology
History 
  • Received October 27, 2015
  • Accepted November 9, 2015
  • Published online January 12, 2016.

Copyright & Usage 
Copyright © 2016 Geddes et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
Editors and / or Reviewers 
  • Andrew J. Alspaugh, Invited Editor, Duke University Medical Center
  • Françoise Dromer, Editor, Institut Pasteur

Author Information

  1. J. M. H. Geddesa,
  2. M. Cazab,
  3. D. Crollb*,
  4. N. Stoynovc,
  5. L. J. Fosterc,
  6. J. W. Kronstada,b
  1. aDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
  2. bMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada
  3. cCentre for High-throughput Biology, University of British Columbia, Vancouver, BC, Canada
  • Address correspondence to J. W. Kronstad, kronstad{at}msl.ubc.ca.
  • ↵* Present address: D. Croll, Institute of Integrative Biology, ETH Zürich, Zürich, Switzerland.

  • Citation Geddes JMH, Caza M, Croll D, Stoynov N, Foster LJ, Kronstad JW. 2016. Analysis of the protein kinase A-regulated proteome of Cryptococcus neoformans identifies a role for the ubiquitin-proteasome pathway in capsule formation. mBio 7(1):e01862-15. doi:10.1128/mBio.01862-15.

  1. This article is a direct contribution from a Fellow of the American Academy of Microbiology.

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Analysis of the Protein Kinase A-Regulated Proteome of Cryptococcus neoformans Identifies a Role for the Ubiquitin-Proteasome Pathway in Capsule Formation
J. M. H. Geddes, M. Caza, D. Croll, N. Stoynov, L. J. Foster, J. W. Kronstad
mBio Jan 2016, 7 (1) e01862-15; DOI: 10.1128/mBio.01862-15

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Analysis of the Protein Kinase A-Regulated Proteome of Cryptococcus neoformans Identifies a Role for the Ubiquitin-Proteasome Pathway in Capsule Formation
J. M. H. Geddes, M. Caza, D. Croll, N. Stoynov, L. J. Foster, J. W. Kronstad
mBio Jan 2016, 7 (1) e01862-15; DOI: 10.1128/mBio.01862-15
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