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Research Article

Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network

Thibault G. Sana, Christoph Baumann, Andreas Merdes, Chantal Soscia, Thomas Rattei, Abderrahman Hachani, Cerith Jones, Keiryn L. Bennett, Alain Filloux, Giulio Superti-Furga, Romé Voulhoux, Sophie Bleves
Dara Frank, Invited Editor, Eric J. Rubin, Editor
Thibault G. Sana
aCNRS & Aix-Marseille Université, Laboratoire d’Ingénierie des Systèmes Macromoléculaires (UMR7255), Institut de Microbiologie de la Méditerranée, Marseille, France
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Christoph Baumann
bResearch Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
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Andreas Merdes
cCentre de Biologie du Développement, Université Paul Sabatier, Toulouse, France
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Chantal Soscia
aCNRS & Aix-Marseille Université, Laboratoire d’Ingénierie des Systèmes Macromoléculaires (UMR7255), Institut de Microbiologie de la Méditerranée, Marseille, France
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Thomas Rattei
dDepartment of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria
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Abderrahman Hachani
aCNRS & Aix-Marseille Université, Laboratoire d’Ingénierie des Systèmes Macromoléculaires (UMR7255), Institut de Microbiologie de la Méditerranée, Marseille, France
eDepartment of Life Sciences, MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom
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Cerith Jones
eDepartment of Life Sciences, MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom
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Keiryn L. Bennett
bResearch Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
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Alain Filloux
eDepartment of Life Sciences, MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom
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Giulio Superti-Furga
bResearch Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
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Romé Voulhoux
aCNRS & Aix-Marseille Université, Laboratoire d’Ingénierie des Systèmes Macromoléculaires (UMR7255), Institut de Microbiologie de la Méditerranée, Marseille, France
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Sophie Bleves
aCNRS & Aix-Marseille Université, Laboratoire d’Ingénierie des Systèmes Macromoléculaires (UMR7255), Institut de Microbiologie de la Méditerranée, Marseille, France
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Dara Frank
Medical College of Wisconsin
Roles: Invited Editor
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Eric J. Rubin
Harvard School of Public Health
Roles: Editor
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DOI: 10.1128/mBio.00712-15
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Article Information

DOI 
https://doi.org/10.1128/mBio.00712-15
PubMed 
26037124

Published By 
American Society for Microbiology
History 
  • Received April 26, 2015
  • Accepted May 6, 2015
  • Published online June 2, 2015.

Copyright & Usage 
Copyright © 2015 Sana et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
Editors and / or Reviewers 
  • Dara Frank, Invited Editor, Medical College of Wisconsin
  • Eric J. Rubin, Editor, Harvard School of Public Health

Author Information

  1. Thibault G. Sanaa*,
  2. Christoph Baumannb,
  3. Andreas Merdesc,
  4. Chantal Sosciaa,
  5. Thomas Ratteid,
  6. Abderrahman Hachania,e,
  7. Cerith Jonese,
  8. Keiryn L. Bennettb,
  9. Alain Fillouxe,
  10. Giulio Superti-Furgab,
  11. Romé Voulhouxa,
  12. Sophie Blevesa
  1. aCNRS & Aix-Marseille Université, Laboratoire d’Ingénierie des Systèmes Macromoléculaires (UMR7255), Institut de Microbiologie de la Méditerranée, Marseille, France
  2. bResearch Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
  3. cCentre de Biologie du Développement, Université Paul Sabatier, Toulouse, France
  4. dDepartment of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria
  5. eDepartment of Life Sciences, MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom
  • Address correspondence to Sophie Bleves, bleves{at}imm.cnrs.fr.
  • ↵* Present address: Thibault G. Sana, Department of Microbiology and Immunology, Stanford University Medical Center, Stanford, California, USA.

  • Citation Sana TG, Baumann C, Merdes A, Soscia C, Rattei T, Hachani A, Jones C, Bennett KL, Filloux A, Superti-Furga G, Voulhoux R, Bleves S. 2015. Internalization of Pseudomonas aeruginosa strain PAO1 into epithelial cells is promoted by interaction of a T6SS effector with the microtubule network. mBio 6(3):e00712-15. doi:10.1128/mBio.00712-15.

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Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network
Thibault G. Sana, Christoph Baumann, Andreas Merdes, Chantal Soscia, Thomas Rattei, Abderrahman Hachani, Cerith Jones, Keiryn L. Bennett, Alain Filloux, Giulio Superti-Furga, Romé Voulhoux, Sophie Bleves
mBio Jun 2015, 6 (3) e00712-15; DOI: 10.1128/mBio.00712-15

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Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network
Thibault G. Sana, Christoph Baumann, Andreas Merdes, Chantal Soscia, Thomas Rattei, Abderrahman Hachani, Cerith Jones, Keiryn L. Bennett, Alain Filloux, Giulio Superti-Furga, Romé Voulhoux, Sophie Bleves
mBio Jun 2015, 6 (3) e00712-15; DOI: 10.1128/mBio.00712-15
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