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Research Article

Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination

Kirk D. C. Jensen, Ana Camejo, Mariane B. Melo, Cynthia Cordeiro, Lindsay Julien, Gijsbert M. Grotenbreg, Eva-Maria Frickel, Hidde L. Ploegh, Lucy Young, Jeroen P. J. Saeij
Louis M. Weiss, Editor
Kirk D. C. Jensen
aDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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Ana Camejo
aDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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Mariane B. Melo
aDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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Cynthia Cordeiro
aDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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Lindsay Julien
aDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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Gijsbert M. Grotenbreg
bDepartment of Microbiology, Department of Biological Sciences, and Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore
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Eva-Maria Frickel
cDivision of Parasitology, MRC National Institute of Medical Research, London, United Kingdom
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Hidde L. Ploegh
dWhitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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Lucy Young
eDepartment of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
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Jeroen P. J. Saeij
aDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
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Louis M. Weiss
Albert Einstein College of Medicine
Roles: Editor
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DOI: 10.1128/mBio.02280-14
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Article Information

DOI 
https://doi.org/10.1128/mBio.02280-14
PubMed 
25714710

Published By 
American Society for Microbiology
History 
  • Received November 8, 2014
  • Accepted January 5, 2015
  • Published online February 24, 2015.

Copyright & Usage 
Copyright © 2015 Jensen et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
Editors and / or Reviewers 
  • Louis M. Weiss, Editor, Albert Einstein College of Medicine

Author Information

  1. Kirk D. C. Jensena*,
  2. Ana Camejoa,
  3. Mariane B. Meloa,
  4. Cynthia Cordeiroa,
  5. Lindsay Juliena,
  6. Gijsbert M. Grotenbregb,
  7. Eva-Maria Frickelc,
  8. Hidde L. Ploeghd,
  9. Lucy Younge,
  10. Jeroen P. J. Saeija
  1. aDepartment of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
  2. bDepartment of Microbiology, Department of Biological Sciences, and Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore
  3. cDivision of Parasitology, MRC National Institute of Medical Research, London, United Kingdom
  4. dWhitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
  5. eDepartment of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA
  • Address correspondence to Jeroen P. J. Saeij, jsaeij{at}mit.edu.
  • ↵* Present address: Kirk D. C. Jensen, School of Natural Sciences, University of California, Merced, Merced, California, USA.

  • K.D.C.J. and A.C. contributed equally to this work.

  • Citation Jensen KDC, Camejo A, Melo MB, Cordeiro C, Julien L, Grotenbreg GM, Frickel E, Ploegh HL, Young L, Saeij JPJ. 2015. Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination. mBio 6(2):e02280-14. doi:10.1128/mBio.02280-14.

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Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination
Kirk D. C. Jensen, Ana Camejo, Mariane B. Melo, Cynthia Cordeiro, Lindsay Julien, Gijsbert M. Grotenbreg, Eva-Maria Frickel, Hidde L. Ploegh, Lucy Young, Jeroen P. J. Saeij
mBio Feb 2015, 6 (2) e02280-14; DOI: 10.1128/mBio.02280-14

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Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination
Kirk D. C. Jensen, Ana Camejo, Mariane B. Melo, Cynthia Cordeiro, Lindsay Julien, Gijsbert M. Grotenbreg, Eva-Maria Frickel, Hidde L. Ploegh, Lucy Young, Jeroen P. J. Saeij
mBio Feb 2015, 6 (2) e02280-14; DOI: 10.1128/mBio.02280-14
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