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Editor's Pick Research Article

Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate

Fernando Almazán, Marta L. DeDiego, Isabel Sola, Sonia Zuñiga, Jose L. Nieto-Torres, Silvia Marquez-Jurado, German Andrés, Luis Enjuanes
Michael J. Buchmeier, Editor
Fernando Almazán
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spaina
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Marta L. DeDiego
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spaina
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Isabel Sola
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spaina
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Sonia Zuñiga
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spaina
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Jose L. Nieto-Torres
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spaina
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Silvia Marquez-Jurado
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spaina
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German Andrés
Centro de Biología Molecular Severo Ochoa (CBMSO-CSIC-UAM), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spainb
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Luis Enjuanes
Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spaina
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Michael J. Buchmeier
University of California, Irvine
Roles: Editor
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DOI: 10.1128/mBio.00650-13
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Article Information

DOI 
https://doi.org/10.1128/mBio.00650-13
PubMed 
24023385

Published By 
American Society for Microbiology
History 
  • Received August 9, 2013
  • Accepted August 12, 2013
  • Published online September 10, 2013.

Copyright & Usage 
Copyright © 2013 Almazán et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
Editors and / or Reviewers 
  • Michael J. Buchmeier, Editor, University of California, Irvine

Author Information

  1. Fernando Almazána,
  2. Marta L. DeDiegoa,
  3. Isabel Solaa,
  4. Sonia Zuñigaa,
  5. Jose L. Nieto-Torresa,
  6. Silvia Marquez-Juradoa,
  7. German Andrésb,
  8. Luis Enjuanesa
  1. Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spaina
  2. Centro de Biología Molecular Severo Ochoa (CBMSO-CSIC-UAM), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spainb
  • Address correspondence to Luis Enjuanes, L.Enjuanes{at}cnb.csic.es.
  • F.A. and M.L.D. contributed equally to this work.

  • Citation Almazán F, DeDiego ML, Sola I, Zuñiga S, Nieto-Torres JL, Marquez-Jurado S, Andrés G, Enjuanes L. 2013. Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate. mBio 4(5):e00650-13. doi:10.1128/mBio.00650-13.

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Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate
Fernando Almazán, Marta L. DeDiego, Isabel Sola, Sonia Zuñiga, Jose L. Nieto-Torres, Silvia Marquez-Jurado, German Andrés, Luis Enjuanes
mBio Sep 2013, 4 (5) e00650-13; DOI: 10.1128/mBio.00650-13

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Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate
Fernando Almazán, Marta L. DeDiego, Isabel Sola, Sonia Zuñiga, Jose L. Nieto-Torres, Silvia Marquez-Jurado, German Andrés, Luis Enjuanes
mBio Sep 2013, 4 (5) e00650-13; DOI: 10.1128/mBio.00650-13
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