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Research Article

A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence

Carl A. Morrow, I. Russel Lee, Eve W. L. Chow, Kate L. Ormerod, Anita Goldinger, Edmond J. Byrnes III, Kirsten Nielsen, Joseph Heitman, Horst Joachim Schirra, James A. Fraser
Judith Berman, Editor
Carl A. Morrow
Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Australiaa
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australiab
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I. Russel Lee
Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Australiaa
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australiab
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Eve W. L. Chow
Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Australiaa
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australiab
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Kate L. Ormerod
Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Australiaa
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australiab
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Anita Goldinger
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australiab
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Edmond J. Byrnes III
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USAc
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Kirsten Nielsen
Department of Microbiology, Medical School, University of Minnesota, Minneapolis, Minnesota, USAd
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Joseph Heitman
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USAe
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Horst Joachim Schirra
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australiab
Centre for Advanced Imaging, University of Queensland, Brisbane, Australiaf
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James A. Fraser
Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Australiaa
School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australiab
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Judith Berman
University of Minnesota
Roles: Editor
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DOI: 10.1128/mBio.00310-11
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Article Information

DOI 
https://doi.org/10.1128/mBio.00310-11
PubMed 
22375073

Published By 
American Society for Microbiology
History 
  • Received December 29, 2011
  • Accepted January 5, 2012
  • Published online February 28, 2012.

Copyright & Usage 
Copyright © 2012 Morrow et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
Editors and / or Reviewers 
  • Judith Berman, Editor, University of Minnesota

Author Information

  1. Carl A. Morrowa,b,
  2. I. Russel Leea,b,
  3. Eve W. L. Chowa,b,
  4. Kate L. Ormeroda,b,
  5. Anita Goldingerb,
  6. Edmond J. Byrnes IIIc,
  7. Kirsten Nielsend,
  8. Joseph Heitmane,
  9. Horst Joachim Schirrab,f,
  10. James A. Frasera,b
  1. Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Australiaa
  2. School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australiab
  3. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USAc
  4. Department of Microbiology, Medical School, University of Minnesota, Minneapolis, Minnesota, USAd
  5. Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USAe
  6. Centre for Advanced Imaging, University of Queensland, Brisbane, Australiaf
  • Address correspondence to James A. Fraser, jafraser{at}uq.edu.au.
  • Citation Morrow CA, et al. 2012. A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence. mBio 3(2):e00310-11. doi:10.1128/mBio.00310-11.

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A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence
Carl A. Morrow, I. Russel Lee, Eve W. L. Chow, Kate L. Ormerod, Anita Goldinger, Edmond J. Byrnes III, Kirsten Nielsen, Joseph Heitman, Horst Joachim Schirra, James A. Fraser
mBio Feb 2012, 3 (2) e00310-11; DOI: 10.1128/mBio.00310-11

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A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence
Carl A. Morrow, I. Russel Lee, Eve W. L. Chow, Kate L. Ormerod, Anita Goldinger, Edmond J. Byrnes III, Kirsten Nielsen, Joseph Heitman, Horst Joachim Schirra, James A. Fraser
mBio Feb 2012, 3 (2) e00310-11; DOI: 10.1128/mBio.00310-11
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