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Research Article

Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites

Yue Li, Xin Yang, Jing Zhang, Tianyi Jiang, Ziyi Zhang, Zhiyi Wang, Mengxue Gong, Liping Zhao, Chenhong Zhang
Colleen M. Cavanaugh, Editor
Yue Li
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
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Xin Yang
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
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Jing Zhang
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
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Tianyi Jiang
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
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Ziyi Zhang
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
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Zhiyi Wang
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
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Mengxue Gong
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
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Liping Zhao
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
bDepartment of Biochemistry and Microbiology and New Jersey Institute for Food, Nutrition and Health, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, New Jersey, USA
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Chenhong Zhang
aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
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  • ORCID record for Chenhong Zhang
Colleen M. Cavanaugh
Harvard University
Roles: Editor
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DOI: 10.1128/mBio.03601-20
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Article Information

DOI 
https://doi.org/10.1128/mBio.03601-20
PubMed 
33785628

Published By 
American Society for Microbiology
History 
  • Received December 25, 2020
  • Accepted February 25, 2021
  • Published online March 30, 2021.

Copyright & Usage 
Copyright © 2021 Li et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Colleen M. Cavanaugh, Editor, Harvard University

Author Information

  1. Yue Lia,
  2. Xin Yanga,
  3. Jing Zhanga,
  4. Tianyi Jianga,
  5. Ziyi Zhanga,
  6. Zhiyi Wanga,
  7. Mengxue Gonga,
  8. Liping Zhaoa,b,
  9. Chenhong Zhanga
  1. aState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China
  2. bDepartment of Biochemistry and Microbiology and New Jersey Institute for Food, Nutrition and Health, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, New Jersey, USA
  • Address correspondence to Chenhong Zhang, zhangchenhong{at}sjtu.edu.cn.
  • Citation Li Y, Yang X, Zhang J, Jiang T, Zhang Z, Wang Z, Gong M, Zhao L, Zhang C. 2021. Ketogenic diets induced glucose intolerance and lipid accumulation in mice with alterations in gut microbiota and metabolites. mBio 12:e03601-20. https://doi.org/10.1128/mBio.03601-20.

  1. This article is a direct contribution from Liping Zhao, a Fellow of the American Academy of Microbiology, who arranged for and secured reviews by Jun Wang, Max-Planck Partner Group for Bioinformatics and Computational Biology, Institute of Microbiology, Chinese Academy of Sciences, and Peng Chen, Southern Medical University, China.

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Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites
Yue Li, Xin Yang, Jing Zhang, Tianyi Jiang, Ziyi Zhang, Zhiyi Wang, Mengxue Gong, Liping Zhao, Chenhong Zhang
mBio Mar 2021, 12 (2) e03601-20; DOI: 10.1128/mBio.03601-20

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Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites
Yue Li, Xin Yang, Jing Zhang, Tianyi Jiang, Ziyi Zhang, Zhiyi Wang, Mengxue Gong, Liping Zhao, Chenhong Zhang
mBio Mar 2021, 12 (2) e03601-20; DOI: 10.1128/mBio.03601-20
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KEYWORDS

ketogenic diet
gut microbiota
fecal metabolites
glucose and lipid metabolism

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