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Research Article | Host-Microbe Biology

Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids

Petra Geiser, Maria Letizia Di Martino, Pilar Samperio Ventayol, Jens Eriksson, Eduardo Sima, Anas Kh. Al-Saffar, David Ahl, Mia Phillipson, Dominic-Luc Webb, Magnus Sundbom, Per M. Hellström, Mikael E. Sellin
Vanessa Sperandio, Editor
Petra Geiser
aScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
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  • ORCID record for Petra Geiser
Maria Letizia Di Martino
aScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
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Pilar Samperio Ventayol
aScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
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Jens Eriksson
aScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
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Eduardo Sima
bDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Anas Kh. Al-Saffar
cDepartment of Medical Sciences, Gastroenterology and Hepatology Unit, Uppsala University, Uppsala, Sweden
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David Ahl
dDepartment of Medical Cell Biology, Uppsala University, Uppsala, Sweden
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Mia Phillipson
dDepartment of Medical Cell Biology, Uppsala University, Uppsala, Sweden
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Dominic-Luc Webb
cDepartment of Medical Sciences, Gastroenterology and Hepatology Unit, Uppsala University, Uppsala, Sweden
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Magnus Sundbom
bDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Per M. Hellström
cDepartment of Medical Sciences, Gastroenterology and Hepatology Unit, Uppsala University, Uppsala, Sweden
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Mikael E. Sellin
aScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
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Vanessa Sperandio
University of Texas Southwestern Medical Center Dallas
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DOI: 10.1128/mBio.02684-20
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Article Information

DOI 
https://doi.org/10.1128/mBio.02684-20
PubMed 
33436434

Published By 
American Society for Microbiology
History 
  • Received September 27, 2020
  • Accepted November 17, 2020
  • Published online January 12, 2021.

Copyright & Usage 
Copyright © 2021 Geiser et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Vanessa Sperandio, Editor, University of Texas Southwestern Medical Center Dallas

Author Information

  1. Petra Geisera,
  2. Maria Letizia Di Martinoa,
  3. Pilar Samperio Ventayola,
  4. Jens Erikssona,
  5. Eduardo Simab,
  6. Anas Kh. Al-Saffarc*,
  7. David Ahld,
  8. Mia Phillipsond,
  9. Dominic-Luc Webbc,
  10. Magnus Sundbomb,
  11. Per M. Hellströmc,
  12. Mikael E. Sellina
  1. aScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
  2. bDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden
  3. cDepartment of Medical Sciences, Gastroenterology and Hepatology Unit, Uppsala University, Uppsala, Sweden
  4. dDepartment of Medical Cell Biology, Uppsala University, Uppsala, Sweden
  • Address correspondence to Mikael E. Sellin, mikael.sellin{at}imbim.uu.se.
  • ↵* Present address: Anas Kh. Al-Saffar, Department of Surgery and Obstetrics, College of Veterinary Medicine, Baghdad University, Baghdad, Iraq.

  • Citation Geiser P, Di Martino ML, Samperio Ventayol P, Eriksson J, Sima E, Al-Saffar AK, Ahl D, Phillipson M, Webb D-L, Sundbom M, Hellström PM, Sellin ME. 2021. Salmonella enterica serovar Typhimurium exploits cycling through epithelial cells to colonize human and murine enteroids. mBio 12:e02684-20. https://doi.org/10.1128/mBio.02684-20.

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Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids
Petra Geiser, Maria Letizia Di Martino, Pilar Samperio Ventayol, Jens Eriksson, Eduardo Sima, Anas Kh. Al-Saffar, David Ahl, Mia Phillipson, Dominic-Luc Webb, Magnus Sundbom, Per M. Hellström, Mikael E. Sellin
mBio Jan 2021, 12 (1) e02684-20; DOI: 10.1128/mBio.02684-20

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Salmonella enterica Serovar Typhimurium Exploits Cycling through Epithelial Cells To Colonize Human and Murine Enteroids
Petra Geiser, Maria Letizia Di Martino, Pilar Samperio Ventayol, Jens Eriksson, Eduardo Sima, Anas Kh. Al-Saffar, David Ahl, Mia Phillipson, Dominic-Luc Webb, Magnus Sundbom, Per M. Hellström, Mikael E. Sellin
mBio Jan 2021, 12 (1) e02684-20; DOI: 10.1128/mBio.02684-20
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KEYWORDS

bioimaging
Enterobacteriaceae
enteroid
gastrointestinal infection
Salmonella

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