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Research Article | Host-Microbe Biology

Intracellular Density of Wolbachia Is Mediated by Host Autophagy and the Bacterial Cytoplasmic Incompatibility Gene cifB in a Cell Type-Dependent Manner in Drosophila melanogaster

Mark Deehan, Weiwei Lin, Benjamin Blum, Andrew Emili, Horacio Frydman
Luis Teixeira, Invited Editor, Margaret J. McFall-Ngai, Editor
Mark Deehan
aDepartment of Biology, Boston University, Boston, Massachusetts, USA
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Weiwei Lin
bCenter for Network Systems Biology, Boston University, Boston, Massachusetts, USA
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Benjamin Blum
bCenter for Network Systems Biology, Boston University, Boston, Massachusetts, USA
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Andrew Emili
bCenter for Network Systems Biology, Boston University, Boston, Massachusetts, USA
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Horacio Frydman
aDepartment of Biology, Boston University, Boston, Massachusetts, USA
cNational Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA
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Luis Teixeira
Instituto Gulbenkian De Ciencia
Roles: Invited Editor
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Margaret J. McFall-Ngai
University of Hawaii at Manoa
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DOI: 10.1128/mBio.02205-20
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Article Information

DOI 
https://doi.org/10.1128/mBio.02205-20
PubMed 
33436431

Published By 
American Society for Microbiology
History 
  • Received August 6, 2020
  • Accepted November 13, 2020
  • Published online January 12, 2021.

Copyright & Usage 
Copyright © 2021 Deehan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Luis Teixeira, Invited Editor, Instituto Gulbenkian De Ciencia
  • Margaret J. McFall-Ngai, Editor, University of Hawaii at Manoa

Author Information

  1. Mark Deehana,
  2. Weiwei Linb,
  3. Benjamin Blumb,
  4. Andrew Emilib,
  5. Horacio Frydmana,c
  1. aDepartment of Biology, Boston University, Boston, Massachusetts, USA
  2. bCenter for Network Systems Biology, Boston University, Boston, Massachusetts, USA
  3. cNational Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA
  • Address correspondence to Mark Deehan, madeehan{at}bu.edu, or Horacio Frydman, hfrydman{at}bu.edu.
  • Citation Deehan M, Lin W, Blum B, Emili A, Frydman H. 2021. Intracellular density of Wolbachia is mediated by host autophagy and the bacterial cytoplasmic incompatibility gene cifB in a cell type-dependent manner in Drosophila melanogaster. mBio 12:e02205-20. https://doi.org/10.1128/mBio.02205-20.

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Intracellular Density of Wolbachia Is Mediated by Host Autophagy and the Bacterial Cytoplasmic Incompatibility Gene cifB in a Cell Type-Dependent Manner in Drosophila melanogaster
Mark Deehan, Weiwei Lin, Benjamin Blum, Andrew Emili, Horacio Frydman
mBio Jan 2021, 12 (1) e02205-20; DOI: 10.1128/mBio.02205-20

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Intracellular Density of Wolbachia Is Mediated by Host Autophagy and the Bacterial Cytoplasmic Incompatibility Gene cifB in a Cell Type-Dependent Manner in Drosophila melanogaster
Mark Deehan, Weiwei Lin, Benjamin Blum, Andrew Emili, Horacio Frydman
mBio Jan 2021, 12 (1) e02205-20; DOI: 10.1128/mBio.02205-20
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KEYWORDS

Wolbachia
autophagy
effector functions
host-pathogen interactions
innate immunity
symbiosis

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