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Research Article | Applied and Environmental Science

Availability of the Molecular Switch XylR Controls Phenotypic Heterogeneity and Lag Duration during Escherichia coli Adaptation from Glucose to Xylose

Manon Barthe, Josué Tchouanti, Pedro Henrique Gomes, Carine Bideaux, Delphine Lestrade, Carl Graham, Jean-Philippe Steyer, Sylvie Meleard, Jérôme Harmand, Nathalie Gorret, Muriel Cocaign-Bousquet, Brice Enjalbert
Pablo Ivan Nikel, Invited Editor, Sang Yup Lee, Editor
Manon Barthe
aTBI, Université de Toulouse, CNRS, INRAE, INSA, Toulouse, France
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Josué Tchouanti
bCMAP, CNRS, Ecole Polytechnique, IP Paris, Palaiseau, France
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Pedro Henrique Gomes
aTBI, Université de Toulouse, CNRS, INRAE, INSA, Toulouse, France
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Carine Bideaux
aTBI, Université de Toulouse, CNRS, INRAE, INSA, Toulouse, France
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Delphine Lestrade
cTWB, Université de Toulouse, CNRS, INRA, INSA, Ramonville-Saint-Agne, France
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Carl Graham
bCMAP, CNRS, Ecole Polytechnique, IP Paris, Palaiseau, France
dInria‡
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Jean-Philippe Steyer
eINRAE, Université de Montpellier, LBE, Narbonne, France
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Sylvie Meleard
bCMAP, CNRS, Ecole Polytechnique, IP Paris, Palaiseau, France
dInria‡
fInstitut Universitaire de France‡
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Jérôme Harmand
eINRAE, Université de Montpellier, LBE, Narbonne, France
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Nathalie Gorret
aTBI, Université de Toulouse, CNRS, INRAE, INSA, Toulouse, France
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Muriel Cocaign-Bousquet
aTBI, Université de Toulouse, CNRS, INRAE, INSA, Toulouse, France
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  • ORCID record for Muriel Cocaign-Bousquet
Brice Enjalbert
aTBI, Université de Toulouse, CNRS, INRAE, INSA, Toulouse, France
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Pablo Ivan Nikel
Novo Nordisk Foundation Center for Biosustainability
Roles: Invited Editor
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Sang Yup Lee
Korea Advanced Institute of Science and Technology
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DOI: 10.1128/mBio.02938-20
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Article Information

DOI 
https://doi.org/10.1128/mBio.02938-20
PubMed 
33443125

Published By 
American Society for Microbiology
History 
  • Received October 20, 2020
  • Accepted November 10, 2020
  • Published online December 22, 2020.

Copyright & Usage 
Copyright © 2020 Barthe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Pablo Ivan Nikel, Invited Editor, Novo Nordisk Foundation Center for Biosustainability
  • Sang Yup Lee, Editor, Korea Advanced Institute of Science and Technology

Author Information

  1. Manon Barthea,
  2. Josué Tchouantib,
  3. Pedro Henrique Gomesa,
  4. Carine Bideauxa,
  5. Delphine Lestradec,
  6. Carl Grahamb,d,
  7. Jean-Philippe Steyere,
  8. Sylvie Meleardb,d,f,
  9. Jérôme Harmande,
  10. Nathalie Gorreta,
  11. Muriel Cocaign-Bousqueta,
  12. Brice Enjalberta
  1. aTBI, Université de Toulouse, CNRS, INRAE, INSA, Toulouse, France
  2. bCMAP, CNRS, Ecole Polytechnique, IP Paris, Palaiseau, France
  3. cTWB, Université de Toulouse, CNRS, INRA, INSA, Ramonville-Saint-Agne, France
  4. dInria‡
  5. eINRAE, Université de Montpellier, LBE, Narbonne, France
  6. fInstitut Universitaire de France‡
  • Address correspondence to Muriel Cocaign-Bousquet, cocaign{at}insa-toulouse.fr.
  • Muriel Cocaign-Bousquet and Brice Enjalbert contributed equally to this work.

  • Citation Barthe M, Tchouanti J, Gomes PH, Bideaux C, Lestrade D, Graham C, Steyer J-P, Meleard S, Harmand J, Gorret N, Cocaign-Bousquet M, Enjalbert B. 2020. Availability of the molecular switch XylR controls phenotypic heterogeneity and lag duration during Escherichia coli adaptation from glucose to xylose. mBio 11:e02938-20. https://doi.org/10.1128/mBio.02938-20.

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Availability of the Molecular Switch XylR Controls Phenotypic Heterogeneity and Lag Duration during Escherichia coli Adaptation from Glucose to Xylose
Manon Barthe, Josué Tchouanti, Pedro Henrique Gomes, Carine Bideaux, Delphine Lestrade, Carl Graham, Jean-Philippe Steyer, Sylvie Meleard, Jérôme Harmand, Nathalie Gorret, Muriel Cocaign-Bousquet, Brice Enjalbert
mBio Dec 2020, 11 (6) e02938-20; DOI: 10.1128/mBio.02938-20

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Availability of the Molecular Switch XylR Controls Phenotypic Heterogeneity and Lag Duration during Escherichia coli Adaptation from Glucose to Xylose
Manon Barthe, Josué Tchouanti, Pedro Henrique Gomes, Carine Bideaux, Delphine Lestrade, Carl Graham, Jean-Philippe Steyer, Sylvie Meleard, Jérôme Harmand, Nathalie Gorret, Muriel Cocaign-Bousquet, Brice Enjalbert
mBio Dec 2020, 11 (6) e02938-20; DOI: 10.1128/mBio.02938-20
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KEYWORDS

adaptation
Escherichia coli
subpopulations
heterogeneity
metabolic transition

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