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Research Article | Molecular Biology and Physiology

Genetic and Biochemical Analysis of Anaerobic Respiration in Bacteroides fragilis and Its Importance In Vivo

Takeshi Ito, Rene Gallegos, Leigh M. Matano, Nicole L. Butler, Noam Hantman, Matthew Kaili, Michael J. Coyne, Laurie E. Comstock, Michael H. Malamy, Blanca Barquera
Derek R. Lovley, Editor
Takeshi Ito
aCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA
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Rene Gallegos
bDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA
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Leigh M. Matano
cDivision of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
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Nicole L. Butler
aCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA
dDepartment of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, New York, USA
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Noam Hantman
aCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA
eDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA
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Matthew Kaili
bDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA
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Michael J. Coyne
cDivision of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
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Laurie E. Comstock
cDivision of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
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Michael H. Malamy
bDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA
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Blanca Barquera
aCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA
eDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA
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Derek R. Lovley
University of Massachusetts Amherst
Roles: Editor
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DOI: 10.1128/mBio.03238-19
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Article Information

DOI 
https://doi.org/10.1128/mBio.03238-19
PubMed 
32019804

Published By 
American Society for Microbiology
History 
  • Received December 10, 2019
  • Accepted December 13, 2019
  • Published online February 4, 2020.

Copyright & Usage 
Copyright © 2020 Ito et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Derek R. Lovley, Editor, University of Massachusetts Amherst

Author Information

  1. Takeshi Itoa,
  2. Rene Gallegosb,
  3. Leigh M. Matanoc,
  4. Nicole L. Butlera,d,
  5. Noam Hantmana,e,
  6. Matthew Kailib,
  7. Michael J. Coynec,
  8. Laurie E. Comstockc,
  9. Michael H. Malamyb,
  10. Blanca Barqueraa,e
  1. aCenter for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA
  2. bDepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA
  3. cDivision of Infectious Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
  4. dDepartment of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, New York, USA
  5. eDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York, USA
  • Address correspondence to Blanca Barquera, barqub{at}rpi.edu.
  • Citation Ito T, Gallegos R, Matano LM, Butler NL, Hantman N, Kaili M, Coyne MJ, Comstock LE, Malamy MH, Barquera B. 2020. Genetic and biochemical analysis of anaerobic respiration in Bacteroides fragilis and its importance in vivo. mBio 11:e03238-19. https://doi.org/10.1128/mBio.03238-19.

  1. This article is a direct contribution from Michael H. Malamy, a Fellow of the American Academy of Microbiology, who arranged for and secured reviews by Dan Fraenkel, Harvard Medical School, and Robert Gennis, University of Illinois at Urbana Champaign.

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Genetic and Biochemical Analysis of Anaerobic Respiration in Bacteroides fragilis and Its Importance In Vivo
Takeshi Ito, Rene Gallegos, Leigh M. Matano, Nicole L. Butler, Noam Hantman, Matthew Kaili, Michael J. Coyne, Laurie E. Comstock, Michael H. Malamy, Blanca Barquera
mBio Feb 2020, 11 (1) e03238-19; DOI: 10.1128/mBio.03238-19

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Genetic and Biochemical Analysis of Anaerobic Respiration in Bacteroides fragilis and Its Importance In Vivo
Takeshi Ito, Rene Gallegos, Leigh M. Matano, Nicole L. Butler, Noam Hantman, Matthew Kaili, Michael J. Coyne, Laurie E. Comstock, Michael H. Malamy, Blanca Barquera
mBio Feb 2020, 11 (1) e03238-19; DOI: 10.1128/mBio.03238-19
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KEYWORDS

Bacteroides fragilis
respiration
NQR
gut microbiota

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