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Research Article | Molecular Biology and Physiology

Combination of Proteogenomics with Peptide De Novo Sequencing Identifies New Genes and Hidden Posttranscriptional Modifications

B. Blank-Landeshammer, I. Teichert, R. Märker, M. Nowrousian, U. Kück, A. Sickmann
Joseph Heitman, Editor
B. Blank-Landeshammer
aLeibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany
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I. Teichert
bAllgemeine und Molekulare Botanik, Ruhr-Universität, Bochum, Germany
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  • ORCID record for I. Teichert
R. Märker
bAllgemeine und Molekulare Botanik, Ruhr-Universität, Bochum, Germany
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M. Nowrousian
bAllgemeine und Molekulare Botanik, Ruhr-Universität, Bochum, Germany
cLehrstuhl für Molekulare und Zelluläre Botanik, Ruhr-Universität, Bochum, Germany
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U. Kück
bAllgemeine und Molekulare Botanik, Ruhr-Universität, Bochum, Germany
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A. Sickmann
aLeibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany
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Joseph Heitman
Duke University
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DOI: 10.1128/mBio.02367-19
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Article Information

DOI 
https://doi.org/10.1128/mBio.02367-19
PubMed 
31615963

Published By 
American Society for Microbiology
History 
  • Received September 11, 2019
  • Accepted September 13, 2019
  • Published online October 15, 2019.

Copyright & Usage 
Copyright © 2019 Blank-Landeshammer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Joseph Heitman, Editor, Duke University

Author Information

  1. B. Blank-Landeshammera,
  2. I. Teichertb,
  3. R. Märkerb,
  4. M. Nowrousianb,c,
  5. U. Kückb,
  6. A. Sickmanna
  1. aLeibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Dortmund, Germany
  2. bAllgemeine und Molekulare Botanik, Ruhr-Universität, Bochum, Germany
  3. cLehrstuhl für Molekulare und Zelluläre Botanik, Ruhr-Universität, Bochum, Germany
  • Address correspondence to U. Kück, ulrich.kueck{at}rub.de, or A. Sickmann, albert.sickmann{at}isas.de.
  • Citation Blank-Landeshammer B, Teichert I, Märker R, Nowrousian M, Kück U, Sickmann A. 2019. Combination of proteogenomics with peptide de novo sequencing identifies new genes and hidden posttranscriptional modifications. mBio 10:e02367-19. https://doi.org/10.1128/mBio.02367-19.

  1. This article is a direct contribution from U. Kück, a Fellow of the American Academy of Microbiology, who arranged for and secured reviews by Oliver Valerius, Georg-August University, and Andrea Urbani, Catholic University of the “Sacred Heart,” Rome.

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Combination of Proteogenomics with Peptide De Novo Sequencing Identifies New Genes and Hidden Posttranscriptional Modifications
B. Blank-Landeshammer, I. Teichert, R. Märker, M. Nowrousian, U. Kück, A. Sickmann
mBio Oct 2019, 10 (5) e02367-19; DOI: 10.1128/mBio.02367-19

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Combination of Proteogenomics with Peptide De Novo Sequencing Identifies New Genes and Hidden Posttranscriptional Modifications
B. Blank-Landeshammer, I. Teichert, R. Märker, M. Nowrousian, U. Kück, A. Sickmann
mBio Oct 2019, 10 (5) e02367-19; DOI: 10.1128/mBio.02367-19
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KEYWORDS

proteogenomics
peptide de novo sequencing
RNA editing
alternative splicing
phylostratigraphy
gene ontology
alternative splice sites
fungal genome
genomics
proteomics

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