ERRATUM
Volume 10, no. 1, e01941-18, 2019, https://doi.org/10.1128/mBio.01941-18. After careful review of Fig. 3, it was noted that for the middle panels of Fig. 3C and D P values instead of r values had been reported. The revised Fig. 3 shown here reports the corrected r values for the correlations of ΔmiR EBV DNA copies/spleen with the percentage of splenic HLA-DR+ CD45RO+ CD4+ T cells (Fig. 3C) and with the percentage of splenic HLA-DR+ CD45RO+ CD8+ T cells (Fig. 3D).
Activation and memory formation of CD8+ T cells correlate with EBV viral load. (A and B) The frequency of splenic HLA-DR+ CD45RO+ CD4+ T cells (A) and splenic HLA-DR+ CD45RO+ CD8+ T cells (B) of huNSG mice infected with either 105 RIU of wt, ΔmiR, or ΔmiR-BART EBV 5 to 7 weeks p.i. or mock huNSG mice (n = 7 to 18/group) was determined by flow cytometry. (C and D) Correlation of the frequencies of activated memory CD4+ (C) and activated memory CD8+ (D) T cells, from panels A and B, respectively, with the splenic endpoint viral DNA loads as determined by qPCR for each infected group. (A and B) Pooled data from 4 wt and ΔmiR-BART and 5 wt and ΔmiR experiments with mean ± SEM. *, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001, Mann-Whitney U test. (C and D) Pooled data from 4 to 7 experiments. *, P ≤ 0.05; **, P ≤ 0.01, Spearman correlation.
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