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Opinion/Hypothesis | Host-Microbe Biology

On the Emergence of Candida auris: Climate Change, Azoles, Swamps, and Birds

Arturo Casadevall, Dimitrios P. Kontoyiannis, Vincent Robert
James W. Kronstad, Editor
Arturo Casadevall
aDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
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Dimitrios P. Kontoyiannis
bDivision of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
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Vincent Robert
cWesterdijk Fungal Biodiversity Institute, Utrecht, Netherlands
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James W. Kronstad
University of British Columbia
Roles: Editor
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DOI: 10.1128/mBio.01397-19
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    FIG 1

    Comparison of thermal tolerance of C. auris and several close relatives. The tree shows that thermal tolerance is not monophyletic to closely related species. Green and red reflect temperature permissiveness and nonpermissiveness, respectively, for growth. Candida spp. with an upper limit of growth at 37°C are not be expected to grow at fever temperatures. Most closely related species manifest lower thermal tolerances than C. auris. The hierarchical tree (unweighted pair group method using average linkages [UPGMA]) is based on pairwise sequence alignments of both internal transcribed spacers and large subunit ribosomal DNA (data obtained and available from the CBS collection at www.westerdijkinstitute.nl).

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    Proposed scheme for the emergence of C. auris.

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On the Emergence of Candida auris: Climate Change, Azoles, Swamps, and Birds
Arturo Casadevall, Dimitrios P. Kontoyiannis, Vincent Robert
mBio Jul 2019, 10 (4) e01397-19; DOI: 10.1128/mBio.01397-19

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On the Emergence of Candida auris: Climate Change, Azoles, Swamps, and Birds
Arturo Casadevall, Dimitrios P. Kontoyiannis, Vincent Robert
mBio Jul 2019, 10 (4) e01397-19; DOI: 10.1128/mBio.01397-19
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KEYWORDS

Candida
climate change
fungus

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