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Research Article | Host-Microbe Biology

Neuroinflammatory Changes in Relation to Cerebrospinal Fluid Viral Load in Simian Immunodeficiency Virus Encephalitis

Dima A. Hammoud, Sanhita Sinharay, Swati Shah, William Schreiber-Stainthorp, Dragan Maric, Siva Muthusamy, Dianne E. Lee, Cheri A. Lee, Falguni Basuli, William C. Reid, Paul Wakim, Kenta Matsuda, Vanessa Hirsch, Avindra Nath, Michele Di Mascio
Shilpa Buch, Invited Editor, Vinayaka R. Prasad, Editor
Dima A. Hammoud
aCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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Sanhita Sinharay
aCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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Swati Shah
aCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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William Schreiber-Stainthorp
aCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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Dragan Maric
bDivision of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
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Siva Muthusamy
aCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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Dianne E. Lee
aCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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Cheri A. Lee
eLaboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
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Falguni Basuli
cImaging Probe Development Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, Maryland, USA
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William C. Reid
aCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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Paul Wakim
dBiostatistics and Clinical Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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Kenta Matsuda
eLaboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
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Vanessa Hirsch
eLaboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
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  • ORCID record for Vanessa Hirsch
Avindra Nath
fSection of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
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Michele Di Mascio
gAIDS Imaging Research Section, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA
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Shilpa Buch
UNMC
Roles: Invited Editor
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Vinayaka R. Prasad
Albert Einstein College of Medicine
Roles: Editor
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DOI: 10.1128/mBio.00970-19
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Article Information

DOI 
https://doi.org/10.1128/mBio.00970-19
PubMed 
31138753

Published By 
American Society for Microbiology
History 
  • Received April 17, 2019
  • Accepted April 29, 2019
  • Published online May 28, 2019.

Copyright & Usage 
This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply.
Editors and / or Reviewers 
  • Shilpa Buch, Invited Editor, UNMC
  • Vinayaka R. Prasad, Editor, Albert Einstein College of Medicine

Author Information

  1. Dima A. Hammouda,
  2. Sanhita Sinharaya,
  3. Swati Shaha,
  4. William Schreiber-Stainthorpa,
  5. Dragan Maricb,
  6. Siva Muthusamya,
  7. Dianne E. Leea,
  8. Cheri A. Leee,
  9. Falguni Basulic,
  10. William C. Reida,
  11. Paul Wakimd,
  12. Kenta Matsudae,
  13. Vanessa Hirsche,
  14. Avindra Nathf,
  15. Michele Di Masciog
  1. aCenter for Infectious Disease Imaging, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
  2. bDivision of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
  3. cImaging Probe Development Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, Maryland, USA
  4. dBiostatistics and Clinical Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
  5. eLaboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
  6. fSection of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
  7. gAIDS Imaging Research Section, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA
  • Address correspondence to Dima A. Hammoud, hammoudd{at}cc.nih.gov.
  • Citation Hammoud DA, Sinharay S, Shah S, Schreiber-Stainthorp W, Maric D, Muthusamy S, Lee DE, Lee CA, Basuli F, Reid WC, Wakim P, Matsuda K, Hirsch V, Nath A, Di Mascio M. 2019. Neuroinflammatory changes in relation to cerebrospinal fluid viral load in simian immunodeficiency virus encephalitis. mBio 10:e00970-19. https://doi.org/10.1128/mBio.00970-19.

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Neuroinflammatory Changes in Relation to Cerebrospinal Fluid Viral Load in Simian Immunodeficiency Virus Encephalitis
Dima A. Hammoud, Sanhita Sinharay, Swati Shah, William Schreiber-Stainthorp, Dragan Maric, Siva Muthusamy, Dianne E. Lee, Cheri A. Lee, Falguni Basuli, William C. Reid, Paul Wakim, Kenta Matsuda, Vanessa Hirsch, Avindra Nath, Michele Di Mascio
mBio May 2019, 10 (3) e00970-19; DOI: 10.1128/mBio.00970-19

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Neuroinflammatory Changes in Relation to Cerebrospinal Fluid Viral Load in Simian Immunodeficiency Virus Encephalitis
Dima A. Hammoud, Sanhita Sinharay, Swati Shah, William Schreiber-Stainthorp, Dragan Maric, Siva Muthusamy, Dianne E. Lee, Cheri A. Lee, Falguni Basuli, William C. Reid, Paul Wakim, Kenta Matsuda, Vanessa Hirsch, Avindra Nath, Michele Di Mascio
mBio May 2019, 10 (3) e00970-19; DOI: 10.1128/mBio.00970-19
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KEYWORDS

DPA714
SIV encephalitis
neuroinflammation
positron emission tomography
rhesus macaques
translocator protein

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