Editor's Pick Research Article | Ecological and Evolutionary Science

De Novo Emergence of Peptides That Confer Antibiotic Resistance

Michael Knopp, Jonina S. Gudmundsdottir, Tobias Nilsson, Finja König, Omar Warsi, Fredrika Rajer, Pia Ädelroth, Dan I. Andersson
Gerard D. Wright, Editor
DOI: 10.1128/mBio.00837-19

Article Information

DOI 
https://doi.org/10.1128/mBio.00837-19
PubMed 
31164464
Published By 
American Society for Microbiology
History 
  • Received April 24, 2019
  • Accepted May 1, 2019
  • Published online June 4, 2019.
Copyright & Usage 
Copyright © 2019 Knopp et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Gerard D. Wright, Editor, McMaster University
  • José Martínez, Solicited external reviewer, Centro Nacional de Biotecnología CSIC
  • Anca Segall, Solicited external reviewer, San Diego State University

Author Information

  1. Michael Knoppa,
  2. Jonina S. Gudmundsdottira,
  3. Tobias Nilssonb,
  4. Finja Königb,
  5. Omar Warsia,
  6. Fredrika Rajera,
  7. Pia Ädelrothb,
  8. Dan I. Anderssona
  1. aDepartment of Medical Biochemistry and Microbiology, Biomedical Center, Uppsala University, Uppsala, Sweden
  2. bDepartment of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden
  • Address correspondence to Dan I. Andersson, Dan.Andersson{at}imbim.uu.se.

  • Citation Knopp M, Gudmundsdottir JS, Nilsson T, König F, Warsi O, Rajer F, Ädelroth P, Andersson DI. 2019. De novo emergence of peptides that confer antibiotic resistance. mBio 10:e00837-19. https://doi.org/10.1128/mBio.00837-19.

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KEYWORDS

Escherichia coli
antibiotic resistance
aminoglycosides
de novo
gene evolution
membrane potential
peptides

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