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Research Article | Molecular Biology and Physiology

BldC Delays Entry into Development To Produce a Sustained Period of Vegetative Growth in Streptomyces venezuelae

Matthew J. Bush, Govind Chandra, Mahmoud M. Al-Bassam, Kim C. Findlay, Mark J. Buttner
Richard Losick, Editor
Matthew J. Bush
Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom
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Govind Chandra
Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom
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Mahmoud M. Al-Bassam
Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom
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Kim C. Findlay
Department of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom
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Mark J. Buttner
Department of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom
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Richard Losick
Harvard University
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Justin Nodwell
University of Toronto
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Joseph McCormick
Duquesne University
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DOI: 10.1128/mBio.02812-18
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Article Information

DOI 
https://doi.org/10.1128/mBio.02812-18
PubMed 
30723132

Published By 
American Society for Microbiology
History 
  • Received December 17, 2018
  • Accepted December 19, 2018
  • Published online February 5, 2019.

Copyright & Usage 
Copyright © 2019 Bush et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Richard Losick, Editor, Harvard University
  • Justin Nodwell, Solicited external reviewer, University of Toronto
  • Joseph McCormick, Solicited external reviewer, Duquesne University

Author Information

  1. Matthew J. Busha,
  2. Govind Chandraa,
  3. Mahmoud M. Al-Bassama*,
  4. Kim C. Findlayb,
  5. Mark J. Buttnera
  1. aDepartment of Molecular Microbiology, John Innes Centre, Norwich, United Kingdom
  2. bDepartment of Cell and Developmental Biology, John Innes Centre, Norwich, United Kingdom
  • Address correspondence to Matthew J. Bush, matt.bush{at}jic.ac.uk, or Mark J. Buttner, mark.buttner{at}jic.ac.uk.
  • ↵* Present address: Mahmoud M. Al-Bassam, Department of Pediatrics, Division of Host-Microbe Systems and Therapeutics, University of California San Diego, La Jolla, California, USA.

  • Citation Bush MJ, Chandra G, Al-Bassam MM, Findlay KC, Buttner MJ. 2019. BldC delays entry into development to produce a sustained period of vegetative growth in Streptomyces venezuelae. mBio 10:e02812-18. https://doi.org/10.1128/mBio.02812-18.

  1. This article is a direct contribution from a Fellow of the American Academy of Microbiology.

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BldC Delays Entry into Development To Produce a Sustained Period of Vegetative Growth in Streptomyces venezuelae
Matthew J. Bush, Govind Chandra, Mahmoud M. Al-Bassam, Kim C. Findlay, Mark J. Buttner
mBio Feb 2019, 10 (1) e02812-18; DOI: 10.1128/mBio.02812-18

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BldC Delays Entry into Development To Produce a Sustained Period of Vegetative Growth in Streptomyces venezuelae
Matthew J. Bush, Govind Chandra, Mahmoud M. Al-Bassam, Kim C. Findlay, Mark J. Buttner
mBio Feb 2019, 10 (1) e02812-18; DOI: 10.1128/mBio.02812-18
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KEYWORDS

cell division
morphological differentiation
sporulation
transcriptional regulation

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