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Editor's Pick Research Article | Molecular Biology and Physiology

CO2 Signaling through the Ptc2-Ssn3 Axis Governs Sustained Hyphal Development of Candida albicans by Reducing Ume6 Phosphorylation and Degradation

Yang Lu, Chang Su, Shatarupa Ray, Yuncong Yuan, Haoping Liu
David Kadosh, Invited Editor, Michael Lorenz, Editor
Yang Lu
aHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China
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Chang Su
aHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China
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Shatarupa Ray
bDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, California, USA
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Yuncong Yuan
aHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China
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Haoping Liu
bDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, California, USA
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David Kadosh
University of Texas Health Science Center at San Antonio
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Michael Lorenz
University of Texas Health Science Center
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DOI: 10.1128/mBio.02320-18
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Article Information

DOI 
https://doi.org/10.1128/mBio.02320-18
PubMed 
30647154

Published By 
American Society for Microbiology
History 
  • Received October 22, 2018
  • Accepted December 7, 2018
  • Published online January 15, 2019.

Copyright & Usage 
Copyright © 2019 Lu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • David Kadosh, Invited Editor, University of Texas Health Science Center at San Antonio
  • Michael Lorenz, Editor, University of Texas Health Science Center

Author Information

  1. Yang Lua,
  2. Chang Sua,
  3. Shatarupa Rayb,
  4. Yuncong Yuana,
  5. Haoping Liub
  1. aHubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China
  2. bDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, California, USA
  • Address correspondence to Yang Lu, ylu7{at}whu.edu.cn, or Haoping Liu, h4liu{at}uci.edu.
  • Y.L. and C.S. contributed equally to this work.

  • Citation Lu Y, Su C, Ray S, Yuan Y, Liu H. 2019. CO2 signaling through the Ptc2-Ssn3 axis governs sustained hyphal development of Candida albicans by reducing Ume6 phosphorylation and degradation. mBio 10:e02320-18. https://doi.org/10.1128/mBio.02320-18.

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CO2 Signaling through the Ptc2-Ssn3 Axis Governs Sustained Hyphal Development of Candida albicans by Reducing Ume6 Phosphorylation and Degradation
Yang Lu, Chang Su, Shatarupa Ray, Yuncong Yuan, Haoping Liu
mBio Jan 2019, 10 (1) e02320-18; DOI: 10.1128/mBio.02320-18

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CO2 Signaling through the Ptc2-Ssn3 Axis Governs Sustained Hyphal Development of Candida albicans by Reducing Ume6 Phosphorylation and Degradation
Yang Lu, Chang Su, Shatarupa Ray, Yuncong Yuan, Haoping Liu
mBio Jan 2019, 10 (1) e02320-18; DOI: 10.1128/mBio.02320-18
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KEYWORDS

Candida albicans
Ssn3/Cdk8
Ume6
carbon dioxide signaling
hyphal development

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